- Possess fluent knowledge in unit operation design, process modeling, process equipment selection, and scale-up methodologies with a drive to challenge existing methods; create and apply cutting edge technology and novel platforms within a time constrained environment.
- Familiarity and working knowledge of modern synthetic organic chemistry.
- Demonstrate high learning agility with the ability to understand and exploit new scientific concepts and methods across multiple disciplines; be able to apply these learnings to a portfolio of small molecule, oligonucleotide, and synthetic peptide modalities.
- Lead and/or supervise the design and development of new synthetic routes for the manufacture of active pharmaceutical ingredients using the most modern technologies, including continuous processing, automated reaction screening, PAT, and modeling and simulation.
- Ability to lead a cross-disciplinary team to evaluate and refine new manufacturing routes, manufacturing technologies, and practices to deliver a challenging portfolio.
- Comfortable with scientific uncertainty and the ability to translate hypotheses into action.
- Encourage team members to take initiative and accountability to achieve goals; draws out and encourages others to share knowledge.
- Provide technical guidance in the scale-up and demonstration of new chemical processes in development and commercial scale equipment. Participate in technology transfer activities to CRO/CMO organizations and Lilly manufacturing to ensure processes are technically sound, well developed and characterized, and safe.
- Design laboratory experimentation in support of process design, definition, optimization, and technology transfer objectives. Ability to generate process (and property design) data based on a fundamental understanding of the underlying physical processes. Utilize advancements in technology (PAT) and modeling platforms to understand and direct experimental protocols.
- Plan and manage short term and long-term development activities. Develop and/or review technical agendas and timelines for project work. Recommend resource allocation to accomplish projects according to plans, communicate progress and propose changes in timeline, objectives, or direction.
- Collaborate with internal and external manufacturing partners to develop robust chemical process that are readily amenable to efficient drug substance manufacturing.
- Collaborate closely with Product Delivery, Project Management, Quality, Manufacturing, and Regulatory scientists to execute and deliver material and information for clinical trials and regulatory submissions.
- Embrace diverse thought, background, and experience to deliver innovative solutions.
- Possess strong communication (oral, written), organizational, and leadership skills.
- Supervise, mentor and develop scientific staff. Ensure continued technical and professional growth of group members, encourage efforts towards excellence and knowledge sharing.
- Active participant in the external environment and the ability to recognize and apply external innovation and across the Lilly synthetic portfolio.
- Possess deep understanding of the external global regulatory climate and emerging requirements. Ability to address key CMC regulatory questions that enable clinical studies and support marketing authorization applications. Minimum Qualifications:
- Ph.D. in chemical engineering or a closely related field with 8+ years of experience; or Master's degree with 15+ years of experience.
- Experience with developing chemical processes the from mid-development cycle (proof of concept) to product commercialization.
- Experience with technical transfer of processes into manufacturing operations. Experience within the pharmaceutical sector is desired; however, other relevant experience may meet expectations. Prior experience in the development of an active ingredient and associated formulated product is acceptable. Relevant industrial sectors include agrochemicals, nutraceuticals, specialty chemicals, and personal care products. Additional Skills/Preferences:
- Experience with authoring regulatory submissions and responding to regulatory questions.
- Experience with modeling and simulation tools, data analytics, and predictive analytics.
- Experience with online and offline analytical techniques and process analytical technologies (PAT).
- Strong technical skills to supply business value.
- Creativity and ability to transform ideas into marketable products and processes.
- Knowledge and experience with management of a technical project.
- Demonstrated leadership capabilities especially in a team environment.
- Demonstrated ability to drive and accept change.
- Demonstrated success in persuasion, influence and negotiation.
- Good interpersonal skills and a sustained tendency for collaboration.
- Ability to prioritize multiple activities and manage ambiguity.
- Ability to influence others to promote a positive work environment.
- Understanding and awareness of the external scientific and regulatory landscape.
- Demonstrated initiative and risk-taking.
- Demonstrated technical proficiency and ability to create ideas for future work plans.
- Established external publication record. Additional Information:
- Travel: 0 -10%
- Position Local: Indianapolis, IN; Lilly Technology Center-North (LTC-N) Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively "Lilly") are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.
Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status. Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women's Network, Working and Living with Disabilities. Learn more about all of our groups. #WeAreLilly -
Quantum Innovations State Center, United StatesOverview · Our client is seeking a Senior Embedded Software Engineer to join their team at State Center. In this role, you will be responsible for developing safety switchgear systems for global players in the mechanical and plant engineering industry, as well as machine users. · ...
-
Digital Transformation- Sr. Systems Analyst
1 week ago
BAXTER Marion, United States Full timeThis is where you save and sustain lives · At Baxter, we are deeply connected by our mission. No matter your role at Baxter, your work makes a positive impact on people around the world. You'll feel a sense of purpose throughout the organization, as we know our work improves out ...
-
Director of Curriculum Development and Community
3 weeks ago
REAL Community Covenant Church Marion, United States**Position Summary** · This position is funded through a Lilly Foundation grant for the Parenting Ambassadors of Reconciliation Initiative (PARI), a proposal made by REAL Community Covenant Church in Marion, Indiana. The PARI will run from Rev. Andrew Morrell, who pastors REAL, w ...
-
Graphic Designer
3 weeks ago
Slingshot Marion, United States**Position: Graphic Designer** · **Department**: Marketing · **Reports to**: VP of Marketing · **Location**: Slingshot Corporate Headquarters - Marion, Indiana or Hybrid · **General Job Description**: · Slingshot is an exciting, dynamic company that collaborates with higher educa ...
-
Registered Nurse
1 week ago
Elite Home Health Marion, United States Full timeWe are hiring for a Regular Schedule Full-Time Registered Nurse or a 7on/7 off Schedule Registered Nurse. · At Elite Home Health, a part of LHC Group, we embrace a culture of caring, belonging, and trust and enjoy the meaningful connections that come from it: for the whole patien ...
-
Registered Nurse Home Health
2 weeks ago
Angels of Mercy Homecare - Marion Marion, United States Full timeWe are hiring for a Registered Nurse to work Full Time in Marion IN · At Angels of Mercy Homecare, a part of LHC Group, we embrace a culture of caring, belonging, and trust and enjoy the meaningful connections that come from it: for the whole patient, their families, each other, ...
-
Home Health RN
3 days ago
LHC-Illinois Home Health Care Marion, United StatesWe are hiring for a full-time, part-time, or prn Home Health Registered Nurse to join our passionate team in Marion, IL · 7 On / 7 Off schedule available for full-time candidates only. This rotation provides our employees with even more flexibility Ask the recruiter for more det ...
-
Attorney
2 weeks ago
State Farm Indianapolis, United States Full timeOverview · We are not just offering a job but a meaningful career Come join our passionate team · As a Fortune 50 company, we hire the best employees to serve our customers, making us a leader in the insurance and financial services industry. State Farm embraces diversity and inc ...
-
Maintenance Technician
1 week ago
BAXTER Marion, United States Full timeThis is where you save and sustain lives · At Baxter, we are deeply connected by our mission. No matter your role at Baxter, your work makes a positive impact on people around the world. You'll feel a sense of purpose throughout the organization, as we know our work improves out ...
-
Legal Secretary
2 weeks ago
State Farm Indianapolis, United States Full timeOverview · We are not just offering a job but a meaningful career Come join our passionate team · As a Fortune 50 company, we hire the best employees to serve our customers, making us a leader in the insurance and financial services industry. State Farm embraces diversity and inc ...
-
BAXTER Marion, United States Full timeThis is where you save and sustain lives · At Baxter, we are deeply connected by our mission. No matter your role at Baxter, your work makes a positive impact on people around the world. You'll feel a sense of purpose throughout the organization, as we know our work improves out ...
-
Sterility Assurance Manager I
3 days ago
BAXTER Marion, United States Full timeThis is where you save and sustain lives · At Baxter, we are deeply connected by our mission. No matter your role at Baxter, your work makes a positive impact on people around the world. You'll feel a sense of purpose throughout the organization, as we know our work improves out ...
-
Goodwill Industries of Central Indiana, Marion, United States_**This is a teaching position for our brand new Excel Center serving Grant County/Marion, IN residents later this summer (the position will hire in June). Are you looking for a more flexible teaching career than the traditional school setting? Do you enjoy being part of a suppor ...
-
Education Coordinator
1 week ago
Boys & Girls Clubs of Fort Wayne Marion, United States**JOB PURPOSE**: · A. To efficiently manage overall daily administrative and operational functions of your Club location with the primary concern for programs and service delivery, supervision and training of staff, facilities management, the overall safety of members and staff, ...
-
Maintenance Technician- HVAC
3 days ago
BAXTER Marion, United States Full timeThis is where you save and sustain lives · At Baxter, we are deeply connected by our mission. No matter your role at Baxter, your work makes a positive impact on people around the world. You'll feel a sense of purpose throughout the organization, as we know our work improves out ...
-
Plant Manager
3 weeks ago
Ardagh Group Marion, United States**Role description**: · The Plant Manager is the leader of the local manufacturing site. This role is responsible for providing proactive equipment machinery support for all capital project and plant needs, focused on improved performance on parts supply and leadership on the man ...
-
Maintenance Supervisor II
2 weeks ago
BAXTER Marion, United States Full timeThis is where you save and sustain lives · At Baxter, we are deeply connected by our mission. No matter your role at Baxter, your work makes a positive impact on people around the world. You'll feel a sense of purpose throughout the organization, as we know our work improves out ...
-
Inpatient Apheresis Registered Nurse
1 week ago
Fresenius Medical Care Indianapolis, United States Full timePOSITION FEATURES: · No experience necessary, we will train you for an exciting and unique specialty in Apheresis. · PURPOSE AND SCOPE: · The Apheresis RN spends 80% or more of their time providing Apheresis treatments providing direct patient care in accordance to company polic ...
-
Production Control Assistant
2 weeks ago
Teledyne e2v Semiconductors Marion, United StatesBe visionary · Teledyne Technologies Incorporated provides enabling technologies for industrial growth markets that require advanced technology and high reliability. These markets include aerospace and defense, factory automation, air and water quality environmental monitoring, e ...
-
Web designer
3 days ago
Sapphire Technologies Marion, IN, United States FreelanceResponsibilities: · - Conceptualization of UI/UX designs using modern methods · - Developing wireframes, mockups, and prototypes tailored to the target audience · - Creating final web designs · - Building HTML templates using modern web technologies (HTML, CSS, Bootstrap, Respons ...
Director - Engineering - Synthetic Molecule Design and Development (SMDD) - Indianapolis, United States - Eli Lilly and Company
Description
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
At Lilly, Synthetic Molecule Design and Development (SMDD) is involved in key activities for the development of synthetic active pharmaceutical ingredients from pre-clinical phases through commercialization of drug substances and drug products. Our scientists and engineers develop key technical and business solutions across the portfolio using their deep technical expertise to accelerate testing of the clinical hypothesis and overall drug development. SMDD delivers on these responsibilities by recognizing diverse talent and cultures are necessary to bring the next generation of life changing medicines to patients.
Our team is looking for experienced, creative, and energetic candidates to lead unit operation development and process optimization of synthetic drug candidates to support clinical trials, regulatory submission, and product commercialization. The position presents an opportunity to lead dynamic teams comprised of process chemists, analytical chemists, formulation scientists, and engineers.
Top candidates for this position will be expected to:
