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    Scientist - IMMEDIATE HIRE - Los Angeles, CA, United States - University of California, Los Angeles

    University of California, Los Angeles
    University of California, Los Angeles Los Angeles, CA, United States

    2 weeks ago

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    Description
    Pediatric Hematology Oncology - Project Scientist -Jonas Lab

    University of California Los Angeles

    The Jonas Lab in the Department of Pediatrics, David Geffen School of Medicine & California NanoSystems Institute at UCLA is seeking a highly motivated project scientist interested in pursuing interdisciplinary research at the interface of nanoscience and regenerative medicine.

    We have a multidisciplinary research team interested in developing new nanotechnology-enabled methods to support the childhood cancer and regenerative medicine research communities in accelerating the discovery and implementation of gene and cellular therapeutic approaches and precision-medicine-based diagnostic strategies.

    With support from the NIH's High-Risk High-Reward Program, our group leverages advances in microfluidics, nanofabrication, and gene editing approaches to explore the ultimate limits of miniaturization.

    These capabilities empower our efforts to create tools that enable stem cell biologists to probe and to interact with stem cells more precisely and empower clinical scientists to apply this knowledge to design and implement new therapies more rapidly and broadly.

    We have multiple postdoctoral positions available immediately to:

    The goal of this NIH-funded project is to establish new manufacturing platforms for gene and stem cell-based therapies directed at pediatric cancers, hematologic disorders, primary immunodeficiencies, and other genetic diseases.

    Design and apply nanocarrier systems to enable cystic fibrosis gene therapies.
    Develop microfluidic liquid biopsy technologies for monitoring treatment response to pediatric sarcomas and other childhood malignancies
    Apply rapid prototyping approaches to fabricate three-dimensionally printed tools for organoid development & toxicity screening of electronic cigarette/vaping products

    PhD, MD/PhD, or equivalent in Bioengineering, Materials Science, Chemistry, Mechanical Engineering, Physics, Electrical Engineering, Molecular Biology or related life science fields of study
    Experience in cell culture, cell biology & molecular biology, immunofluorescence/flow cytometry, next generation sequencing techniques, gene editing methods, and biochemical techniques desired
    Ability to multitask and quickly adapt to new research challenges
    Excellent communication skills and ability to work in a diverse, interdisciplinary research environment and to interact with computational and experimental scientists
    Ability to function independently in the laboratory and lead project teams
    Desire to engage and mentor graduate, medical, and undergraduate students across different academic disciplines Skills:
    Experience with micro/nanofabrication techniques, including photolithography and three-dimensional printing for rapid prototyping and application of microfluidic systems
    Experience in the design of computer models/simulations for prototyping of project-specific devices
    Experience with cell culture, transfection, immunofluorescence/flow cytometry, and biochemical and molecular biology techniques
    Experience in the development and characterization of gene editing reagents, PCR, cloning, and/or Next-Generation sequencing desired
    Working knowledge of laboratory notebook management and data management
    Knowledge of aseptic and laboratory technique
    Meticulous organizational and data analysis skills Duties and Responsibilities:
    Ability to work and lead more independently and multitask projects more extensively
    Leadership and coordination of project activities and collaborative efforts. Oversee development of technology platforms for cellular therapy manufacturing, nanoparticle vehicles, organoids, and/or liquid biopsy diagnostic tests and characterization of cell products resulting from this work
    Ability to multitask and contribute to and oversee multiple collaborative projects efficiently and effectively
    Supervision, mentorship, and teaching of undergraduate, graduate, and medical students, new postdoctoral trainees, and staff research associates in the lab

    Required to communicate well with other scientists, regulatory personnel, biotech companies, sponsored research organizations, and other scientific personnel worldwide.

    Supervise preparation of manuscripts for publication of results of independent and collaborative laboratory research. The candidate will also provide support in publishing the results of various projects.
    Participate in laboratory meetings, educational sessions, general and specific safety training and other training sessions
    Assist and work with PI directly to identify new opportunities and research directions for the laboratory
    Assist PI in preparation of grant proposals and progress reports, as needed.
    Desire to work toward transitioning to independence as an early-stage scientific investigator
    Performs other duties and laboratory responsibilities as requested.

    Interested candidates can apply online at Cultural North Star The shared values of the DGSOM are expressed in the Cultural North Star, which was developed by members of our community and affirms our unswerving commitment to doing what's right, making things better, and being kind.

    Anti-Racism Roadmap The David Geffen School of Medicine Anti-racism roadmap is our co-created path to ensuring racial justice, equity, diversity and inclusion.

    All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.

    For the complete University of California nondiscrimination and affirmative action policy, see:
    UC Nondiscrimination & Affirmative Action Policy, jeid-c4e7a99d5c295e4ea0007b7a7ad0930b]]
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