Senior Principal Scientist, AI/ML Antibody Design - Tarrytown - Regeneron Pharmaceuticals, Inc

    Regeneron Pharmaceuticals, Inc
    Regeneron Pharmaceuticals, Inc Tarrytown

    1 day ago

    $178,000 - $223,000 per year *
    Description

    Overview

    We are seeking a highly talented and motivated Senior Principal Scientist specializing in AI Machine Learning to lead the design and engineering of our next-generation antibody-based protein therapies.

    The ideal candidate shall have a strong background and passion in both computational biology, with expertise in programming, large language models, in silico protein design tools, and knowledge in structural biology and antibody engineering.

    You will help drive both internal development and external partnership to create/validate AI/ML tools to enable our quest for next-gen antibody therapies.

    By closely working with antibody engineers, structural biologists and AI/ML scientists from a cross-functional team, you have a unique opportunity to shape the future of our AI/ML strategy and deliver on future biotherapies from our state-of-the-art research facilities.

    Key Responsibilities

    1. Utilize AI and machine learning techniques to design novel antibodies and bi/multi-specific antibodies that would be challenging to achieve from screening
    2. Develop novel AI and machine learning tools to enable de novo antibody discovery with unique properties and in silico co-optimization of affinity, expression, stability and PK/half-life.
    3. Apply deep learning and generative AI techniques to train/enhance LLM or other relevant language models using internal datasets
    4. Use in silico protein/antibody engineering design tools such as Rosetta to drive for structure-based design and engineering
    5. Leverage deep target biology from broad therapeutic areas to enable desired novel MoAs through molecular design
    6. Collaborate and support scientists from antibody engineering, therapeutic areas and other tech centers with biotherapeutic design
    7. Guide and lead AI/ML scientists across multiple functions to have a synergized AI/ML strategy and drive sustained delivery of novel molecular entities to pipeline
    8. Serve as an expert in computational biologic design to keep up with the latest advancements in AI, machine learning, and protein engineering fields
    9. Maintain data analysis and records in well-organized fashion
    10. Presentation data clearly to teams and managements

    Requirements

    This role may be for you if:

    1. You are a result-driven innovator and a problem solver
    2. You have a strong background in computational biology, programming, deep learning algorithms, structural biology and protein engineering
    3. You have expertise with advanced machine learning models related to antibody engineering, such as language model, geometric deep learning, generative model and multi-modal model
    4. You have proficiency in programming languages such as Python, R and C++
    5. You have competence to work with large dataset and cloud computing infrastructure
    6. You can efficiently coordinate multiple projects in a collaborative environment
    7. You have strong organizational, time-management, and presentation skills
    8. You enjoy working in a fast-paced, innovative and cross-functional team

    Qualifications

    To be considered for this opportunity, you must have a PhD in Computational Biology, Bioinformatics, Computer Science, Structural Biology or a related field, with 7-10 years of relevant experience.

    You must have a strong track record of innovation and research accomplishments in developing AI/ML methods and using deep learning tools to successfully solve antibody/protein engineering challenges.

    Experience in using structural modeling and design tools (e.g. Rosetta) is strongly preferred.

    Experience in constructing DNA and protein production for screening in silico design is preferred.

    * This salary range is an estimation made by beBee

  • Principal Scientist, Protein Design and Antibody Engineering

    3 days ago

    Regeneron Pharmaceuticals Inc Tarrytown $126 - $206,900 per year

    · We are seeking a highly skilled and motivated Principal Scientist with expertise in computational biology, protein structural modeling and engineering, and artificial intelligence to join the Bispecific Antibodies Group. This role focuses on designing and optimizing novel anti ...

  • Senior Principal Scientist, AI/ML Antibody Design

    3 days ago

    Regeneron Pharmaceuticals Inc Tarrytown $148 - $241,900 per year

    · We are seeking a highly talented and motivated Senior Principal Scientist specializing in AI Machine Learning to lead the design and engineering of our next-generation antibody-based protein therapies. The ideal candidate shall have a strong background and passion in both comp ...

  • Senior Principal Scientist, AI/ML Antibody Design

    1 week ago

    Regeneron Pharmaceuticals, Inc Village of Tarrytown

    Senior Principal Scientist AI/ML Antibody Design and Engineering · We are seeking a highly talented and motivated Senior Principal Scientist specializing in AI Machine Learning to lead the design and engineering of our next-generation antibody-based protein therapies. · Key Respo ...

  • Principal Scientist, Protein Design and Antibody Engineering

    1 day ago

    BioSpace Tarrytown

    Job Details · We are seeking a highly skilled and motivated Principal Scientist with expertise in computational biology, protein structural modeling and engineering, and artificial intelligence to join the Bispecific Antibodies Group. This role focuses on designing and optimizing ...

  • Senior Principal Scientist, AI/ML Antibody Design

    1 week ago

    BioSpace Village of Tarrytown

    Senior Principal Scientist, AI/ML Antibody Design & Engineering · We are seeking a highly talented and motivated Senior Principal Scientist specializing in AI Machine Learning to lead the design and engineering of our next-generation antibody-based protein therapies. · Job Descri ...

  • Senior Principal Scientist, AI/ML Antibody Design

    1 week ago

    Regeneron Village of Tarrytown

    Senior Principal Scientist, AI/ML Antibody Design & Engineering · The Regeneron Way is a culture that values innovation and collaboration. We are seeking a highly talented and motivated Senior Principal Scientist specializing in AI Machine Learning to lead the design and engineer ...

  • Senior Principal Scientist, AI/ML Antibody Design

    18 hours ago

    BioSpace Tarrytown

    Job Details · We are seeking a highly talented and motivated Senior Principal Scientist specializing in AI Machine Learning to lead the design and engineering of our next-generation antibody-based protein therapies. The ideal candidate shall have a strong background and passion i ...

  • Scientist- Viral Delivery Technologies

    1 week ago

    Only for registered members Tarrytown Full time $92,500 - $151,100

    We are seeking a highly motivated Scientist to support the development of an antibody-retargeted Adeno-associated virus (AAV) delivery platform within our Viral Delivery Technologies group. You will support the design, characterization, and in vitro validation of novel AAVs, furt ...

  • Sr. Scientist- Histology Core

    1 week ago

    Only for registered members Tarrytown Full time $108,300 - $176,700

    We are seeking a highly motivated, innovative, and collaborative Senior Scientist to join our Pre-clinical Histology Core within the Imaging Sciences department. In this role, you will partner with research scientists to understand their scientific questions and drive histology e ...

  • Principle Scientist

    3 days ago

    Regeneron Pharmaceuticals Inc Tarrytown FlexTime $126 - $206,900 per year

    · We are seeking a highly motivated Principal Scientist within the Formulation Development Group (FDG) of Regeneron Pharmaceutical Inc. at Tarrytown, NY. The Principal Scientist leads formulation and drug product development that may include candidate screening and selection for ...

  • Senior Director, Assistant General Counsel, Patent Attorney

    3 days ago

    Regeneron Pharmaceuticals Inc Tarrytown FlexTime $238,000 - $397,300 per year

    · The Senior Director, AGC Patent Attorney will oversee and manage the company's intellectual property in the field of genetic medicines. These medicines are designed to alter genomes, enabling gene expression, silencing, or editing, and hold promise for treating a variety of di ...

  • Senior Associate Scientist, Immunology

    3 days ago

    Regeneron Pharmaceuticals Inc Tarrytown FlexTime $79,000 - $129,100 per year

    · We are seeking a dedicated, self-motivated Senior Associate Scientist to join our technology development and drug discovery efforts in the areas of immune tolerance, cell-based immune therapies and hematopoietic stem cell transplant biology. VelocImmune (VI) Next is an innovat ...

  • Director, Patent Attorney – Genetics Medicines

    3 days ago

    Regeneron Pharmaceuticals Inc Tarrytown FlexTime $202 - $336,600 per year

    · The Director, Patent Attorney will partner with our research teams in development, protection, and management of the company's valuable intellectual property in the field of genetic medicines. These genetic medicines are designed to alter genomes and/or gene expression, enabli ...

  • Director, Patent Attorney – Genetics Medicines

    1 week ago

    Only for registered members Tarrytown Full time $202,000 - $336,600

    The Director, Patent Attorney will partner with our research teams in development, protection, and management of the company's valuable intellectual property in the field of genetic medicines. These genetic medicines are designed to alter genomes and/or gene expression, enabling ...

  • Senior Scientist- Proteogenomics Approaches for Novel Antigen Discovery

    3 days ago

    Regeneron Pharmaceuticals Inc Tarrytown $108 - $176,700 per year

    · We are seeking a highly motivated Senior Scientist who will use our pioneering facilities and technology to perform qualitative and quantitative mass spectrometry experiments focusing on autoimmune, infectious disease, and oncology targets for novel Immunotherapeutics such as ...

  • Process Development Engineer II

    1 week ago

    Only for registered members Tarrytown Full time $92,500 - $151,100

    Regeneron's Preclinical Manufacturing & Process Development group (PMPD), located in Tarrytown NY, is seeking a hardworking and dynamic Process Development Engineer II for its new Synthetic and Bioconjugation Scale-up Technologies (SBST) group. · Enjoy working in the lab to advan ...

  • Principal Scientist- Infectious Disease

    6 days ago

    BioSpace Tarrytown, NY Full time $126,700 - $206,900 per year

    Job Description · We are seeking a highly skilled, motivated, and innovative Principal Scientist to lead the development of antiviral immunological therapies. · Lead and manage research projects, either directly or by mentoring team members. · Design and conduct T cell characteri ...

  • Process Development Engineer II

    2 days ago

    Regeneron Pharmaceuticals Tarrytown 92500 - 151100 per year

    Regeneron's Preclinical Manufacturing & Process Development group (PMPD) is seeking a hardworking and dynamic Process Development Engineer. In this role, you will develop conjugation and purification processes for bioconjugation of proteins to small-molecules. · Key Responsibilit ...

  • Sr Scientist, Protein Biochemistry

    10 hours ago

    Regeneron Pharmaceuticals, Inc Tarrytown Full time $143,000 - $194,000 per year

    As a Senior Scientist in our Protein Biochemistry team at Regeneron Pharmaceuticals Inc., you will play a critical role in implementing innovative biophysical assessment strategies to support various drug candidate modalities. · Key Responsibilities: · Design, develop, and execut ...

  • Principal Scientist- Infectious Disease

    5 days ago

    Regeneron Tarrytown, NY Full time 126700 - 206900 per year

    Role Overview · We are seeking a highly skilled, motivated, and innovative Principal Scientist to lead the development of antiviral immunological therapies. · Responsibilities · Lead and manage research projects, either directly or by mentoring team members. · Design and conduct ...

Jobs
>
Tarrytown