Research Scientist - San Mateo - GILEAD

    GILEAD
    GILEAD San Mateo

    17 hours ago

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    Description

    We are Gilead, a company that creates a healthier world for all people. Our mission is to tackle the world's biggest health challenges and develop therapies that improve lives. We achieve this through collaboration, determination, and a relentless drive to make a difference.

    Job Description

    Gilead Sciences is seeking a Research Scientist to join our Oncology Research group. The successful candidate will lead and contribute to the discovery, research, and development of novel therapeutic agents to address unmet medical needs of cancer patients.

    Key Responsibilities:

    • Lead the initiation and/or advancement of oncology projects into the pipeline using in vitro and in vivo methodologies.
    • Participate in nomination of new targets.
    • Direct, independently plan, execute, analyze, and interpret complex experiments to identify or validate novel targets, elucidate target biology, elucidate drug candidates mechanism of action.
    • Develop assays to measure pharmacodynamic markers, kinetics of drug response.
    • Train and mentor junior scientists or direct members of project teams in the initiation and execution of experimental plans.
    • Manage multiple projects simultaneously and work cross-functionally with colleagues in the oncology, in vivo pharmacology, bioinformatics, medicinal chemistry, DMPK and other relevant functions.
    • Proactively evaluate new technologies and implement new approaches to enhance our understanding of disease mechanisms.
    • Presents research findings and recommendations to leadership, author and contribute to research reports, manuscripts, IND and patent filings.
    • Think critically and creatively, work independently as well as a part of collaborative teams.
    • Have strong organizational and planning skills.
    • Cultivate a culture that embraces scientific excellence, urgency, partnerships with key stakeholders, continuous learning and improvement, taking proactive role in personal growth and development.

    Basic Qualifications:

    • PhD degree in related life sciences.
    • Master's degree in related life sciences and 4+ years of experience in cell biology, molecular biology, or biochemistry in biotechnology or pharmaceutical industry OR
    • Bachelor's degree in related life sciences and 6+ years of experience in cell biology, molecular biology, or biochemistry in biotechnology or pharmaceutical industry.

    Preferred Qualifications:

    • PhD degree in Cell Biology, Molecular Biology, or Immunology with 3+ years postdoctoral training in cancer cell biology supported by impactful publications.
    • Deep and broad knowledge of cancer biology, oncology targets and signaling pathways, demonstrated scientific rigor, independence and scientific achievements.
    • Demonstrated experience in elucidating biology of targets in oncology utilizing genetic and pharmacological tools.
    • Passionate about hands-on experimental work, able to critically evaluate experimental results and make data-driven decisions.
    • Excellent technical skills, extensive experience in broad range of molecular and cell biology techniques and superb knowledge of various experimental methodologies including but not limited to gene expression platforms, knockdown, knockout, knock-in and over-expression of genes, flow cytometry, MSD ELISA, high-content imaging.
    • Technical skills applicable to chromatin biology is a plus.
    • Demonstrated working experience with in vivo tumor models is a plus.
    • Attention to quality and details, with excellent record keeping skills.
    • Excellent communication and interpersonal skills.
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