- Experienced pathologist (MD, DVM) with relevant post-doctoral academic, clinical and/or industry pathology experience -required
- Board certification in pathology (anatomic, clinical, combined, with or without additional specialization) - required
- PhD in relevant field of science -preferred, but not required
- The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
- We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
- This job is eligible to participate in our short-term incentive programs.
- This job is eligible to participate in our long-term incentive programs.
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Pathologist, Director, Precision Medicine Pathology - North Chicago, United States - AbbVie
Description
Job Description
Job DescriptionCompany DescriptionAbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.
Job DescriptionPrecision Medicine Pathology supports projects from Discovery through Companion Diagnostics across therapeutic areas. Pathologists are deployed to projects to provide expertise in human disease pathology, experimental pathology support and contribute to the development and interpretation of tissue-based assays.
Specific responsibilities can include:
• Contribute to or lead efforts to identify tissue-based biomarkers, including their
characterization, validation and use in the development of tissue-based assays.
• Contribute to or lead the design and interpretation of tissue-based studies investigating
aspects such as target biology, drug MOA, target pathway activation, pharmacodynamic
effects, biomarker prevalence, or drug distribution.
• Contribute to the design, validation and deployment of pathology assays, including the
determination of assay parameters such as specificity and sensitivity.
• Develop, validate and implement scoring paradigms for tissue-based assays
• Design, implement and oversee pathology-based biomarker and diagnostic testing,
including data analysis:
o Direct the development, outsourcing and validation of clinically applicable tissue-based
assays. Assist in the development of assay protocols as needed.
o Write the relevant pathology-based biomarker and diagnostics testing sections in drug
development and registration documents such as clinical study protocols, clinical study
reports, investigator brochures, and regulatory submission packages (INDs, NDA's,
BLA's).
• Provide pathology input to project teams and ensure access to state-of-the-art tissue-based
techniques and samples for target pathway evaluation in human disease:
o Implement technologies and/or methodologies via a combination of in-house efforts
and the use of CROs or other external expertise using techniques such as in situ
hybridization, immunohistochemistry (including multiplexed), image analysis, RNAseq,
qPCR, etc.
o Evaluate the scientific basis and clinical applicability of the proposed assays, their
validation status and any related technical issues.
o Assume responsibility for the assessment and scoring of specimens and the preparation
of reports summarizing the data, analysis and interpretation of findings.
o Collaborate with project teams from concept to reagent generation to quantitation and
approval plan for CDx as needed.
• Participate in the evaluation of external licensing or collaborative opportunities (including
CDx collaborations) and oversee internal components of shared programs.
• Participate in or lead project development teams or sub-teams. Coordinate with
appropriate team members to advance projects efficiently.
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company's sole and absolute discretion, consistent with applicable law.
AbbVie is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVie's policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.
