- Design and execute binding characterization studies using SPR (Biacore S200 and 8K+).
- Conduct routine compound screening and mechanistic studies using biophysical assays (e.g., nanoDSF, DLS, Spectral Shift).
- Manage and coordinate outsourced biophysical studies with CROs.
- Analyze and interpret data to support SAR lead optimization across multiple projects.
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We are seeking a highly motivated and skilled Biophysicist with hands-on experience in small molecule drug discovery to join our dynamic Lead Discovery group. · ...
South San Francisco, CA1 month ago
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· About Astera: · Astera is a private foundation on a mission to steer science and technology toward an abundant future. We believe the coming years will bring an era of unprecedented scientific and technological advancement as exponential progress in AI converges with central a ...
Emeryville $100,000 - $180,000 (USD) Full time1 day ago
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+Biophysical Characterization&Who We AreBioMarin is a global biotechnology company that relentlessly pursues bold science to translate genetic discoveries into new medicines that advance the future of human health. · We enlist the best of the best – people with the right technica ...
San Rafael1 month ago
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We are seeking a Senior Scientist to lead analytical strategy and experimental design for therapeutic proteins and their bioconjugates—particularly enzyme- and antibody-based platforms. The ideal candidate will have a Ph.D. in Biophysics, Biochemistry, Pharmaceutical Sciences or ...
San Rafael1 month ago
- Work in company
Scientist 2, Separations and Biophysical Characterization
Only for registered members
DESCRIPTION · Who We Are · BioMarin is a global biotechnology company that relentlessly pursues bold science to translate genetic discoveries into new medicines that advance the future of human health. · Since our founding in 1997, we have applied our scientific expertise in un ...
Novato, CA1 week ago
- Work in company
Senior / Principal Scientist, Protein Analytics (Biophysical Characterization & Analytical Methods)
Only for registered members
Position Summary · We are a stealth biotechnology company developing precision therapeutics for cardiovascular disease, seeking a highly skilled and hands-on Senior to Principal Scientist to join our Protein Science team. · This role will focus on analytical and biophysical chara ...
South San Francisco1 week ago
- Work in company
Senior / Principal Scientist, Protein Analytics (Biophysical Characterization & Analytical Methods)
Only for registered members
Position Summary · We are a stealth biotechnology company developing precision therapeutics for cardiovascular disease, seeking a highly skilled and hands-on Senior to Principal Scientist to join our Protein Science team. · This role will focus on analytical and biophysical chara ...
South San Francisco, CA1 week ago
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Benefits: · 401(k) · Bonus based on performance · Dental insurance · Health insurance · Stock options plan · Vision insurance · Senior / Principal Scientist, Protein Analytics (Biophysical Characterization & Analytical Methods) · Position Summary · We are a stealth biotechnology ...
South San Francisco, CA2 weeks ago
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We're Hiring: Scientist II · We are seeking a motivated and detail-oriented Scientist II to join our dynamic team in South San Francisco, CA. The ideal candidate will possess strong analytical skills and a passion for scientific research, contributing to innovative projects that ...
South San Francisco, CA $70,000 - $115,000 (USD) per year5 days ago
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Vilya is a computational biotechnology company creating a novel class of medicines to precisely target disease biology. We believe computational approaches are an integral, if not foundational, component of drug discovery and development. Our platform is built on ground-breaking ...
South San Francisco, CA2 hours ago
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We're Hiring: Scientist II · We are seeking a motivated and detail-oriented Scientist II to join our dynamic team in South San Francisco, CA. The ideal candidate will possess strong analytical skills and a passion for scientific research, contributing to innovative projects that ...
South San Francisco $70,000 - $115,000 (USD) per year5 days ago
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JLSa2, founded in 2024, is a well-resourced, seed-stage venture backed company located in South San Francisco currently developing a robust pipeline of novel protein-drug conjugate therapies to better address human metabolic diseases and other non-oncology related diseases. · The ...
South San Francisco, CA3 hours ago
- Work in company
Scientist/Senior Scientist, Computational Antibody Engineering
Only for registered members
We are looking for a Scientist or Senior Scientist in computational antibody engineering to support efforts spanning from structure-based epitope analysis for target prioritization to design and optimization of next-generation multispecific T-cell engaging immunotherapies. You wi ...
South San Francisco $140,000 - $155,000 (USD) Full time1 week ago
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· Scientist Antibody Discovery needs significant experience in antibody discovery and protein engineering by using single B cell cloning, hybridoma, or phage/yeast display techniques · Scientist Antibody Discovery requires: · PhD in Biochemistry, Biomedical/Chemical Engineering ...
South San Francisco, California, United States22 hours ago
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Job Title: Scientist II - Bioconjugation and Delivery · Location: South San Francisco, CA Fully on-site) · Duration: 04/06/2026 to 04/05/2027 · Description · ** To support Protein Bioconjugation and Conjugate Characterization efforts within the Protein Sciences organization · ** ...
South San Francisco12 hours ago
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We're Hiring: Scientist II · We are looking for a motivated and detail-oriented Scientist II to join our dynamic research team in South San Francisco. The ideal candidate will have at least 1 year of experience in a laboratory setting, contributing to innovative projects that dr ...
South San Francisco, CA $70,000 - $115,000 (USD) per year4 days ago
- Work in company
Postdoctoral Fellow- Biological Chemistry, Kirchhofer lab
Only for registered members
We are seeking a highly motivated postdoctoral fellow to join the laboratory of Dr. Daniel Kirchhofer in the Department of Biological Chemistry at Genentech. · This position offers an exciting opportunity to use state-of-the-art peptide display technologies - including phage and ...
South San Francisco, CA3 weeks ago
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Vilya is a computational biotechnology company creating a novel class of medicines to precisely target disease biology. We believe computational approaches are an integral, if not foundational, component of drug discovery and development. Our platform is built on ground-breaking ...
South San Francisco $25 - $45 (USD)1 day ago
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We're Hiring: Scientist II · We are seeking a motivated and detail-oriented Scientist II to join our dynamic team in South San Francisco, CA. The ideal candidate will possess strong analytical skills and a passion for scientific research, contributing to innovative projects that ...
South San Francisco $70,000 - $115,000 (USD) per year5 days ago
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Job Title · : Scientist (Oligonucleotide) · Location · : South San Francisco, CA Fully on-site) · Duration · : 04/06/2026 to 04/05/2027 · Description · ** To support Protein Bioconjugation and Conjugate Characterization efforts within the Protein Sciences organization · ** To con ...
South San Francisco, CA $115,000 - $180,000 (USD) per year6 days ago
Senior Research Scientist, Biophysics - South San Francisco - Yoh, A Day & Zimmermann Company
Description
Job Title: Senior Research Scientist, Biophysics
We are seeking a skilled and driven Senior Research Scientist, Biophysics to join our collaborative Lead Discovery team. This is a lab-based role focused on the biophysical and mechanistic characterization of small molecule-protein interactions to support our drug discovery pipeline.
A successful candidate will have hands-on industry experience in designing executing binding characterization studies using SPR as well as other relevant expertise listed below under qualifications.
Qualifications
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Sr. Research Scientist Biophysics
Only for registered members South San Francisco, CA
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Scientist - Computational Biophysics
Full time Only for registered members Emeryville
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Senior Scientist 1, Biophysical Characterization
Only for registered members San Rafael
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Senior Scientist 1, Biophysical Characterization
Only for registered members San Rafael
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Scientist 2, Separations and Biophysical Characterization
Only for registered members Novato, CA
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Senior / Principal Scientist, Protein Analytics (Biophysical Characterization & Analytical Methods)
Only for registered members South San Francisco
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Senior / Principal Scientist, Protein Analytics (Biophysical Characterization & Analytical Methods)
Only for registered members South San Francisco, CA
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Senior or Principal Scientist, Protein Analytics
Only for registered members South San Francisco, CA
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Scientist II (39737)
Only for registered members South San Francisco, CA
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Intern - Structural Biology
Only for registered members South San Francisco, CA
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Scientist II (39737)
Tap Growth ai- South San Francisco
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Senior Scientist, Protein
Only for registered members South San Francisco, CA
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Scientist/Senior Scientist, Computational Antibody Engineering
Full time Only for registered members South San Francisco
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Scientist Antibody Discovery
Only for registered members South San Francisco, California, United States
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Scientist
Aequor- South San Francisco
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Scientist II
Only for registered members South San Francisco, CA
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Postdoctoral Fellow- Biological Chemistry, Kirchhofer lab
Only for registered members South San Francisco, CA
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Intern - Structural Biology
Only for registered members South San Francisco
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Scientist II (39737)
Only for registered members South San Francisco
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Senior Scientist
Only for registered members South San Francisco, CA