Roni Amiel

I am a hybrid CEO / COO / CIO / CTO with more than 25 years leading transformation across healthcare, MedTech, diagnostics, life sciences, and AI-driven SaaS platforms. My work centers on building secure, AI-powered, clinically aligned enterprises that scale reliably, perform consistently, and deliver measurable financial and clinical outcomes.

Across multiple PE-backed portfolios, global health systems, and high-growth AI companies, I have led organizations through 0→1 product creation, 1→10 scale, operational turnarounds, M&A integration, and enterprise modernization. This includes delivering:

40% EBITDA, 84% gross margins, 37% operating margin, and major productivity gains

$120M+ capital raised, $90M+ M&A, and a 10× MOIC exit

FDA-cleared SaMD diagnostics, national CPT reimbursement, and global regulatory approvals (CLIA, CE, MHRA)

National and global scale across 50 states and 13 countries

My differentiator is the ability to operate simultaneously as strategist, technologist, operator, and security leader, integrating:

Enterprise modernization (cloud, data, AI/ML, interoperability)

Cybersecurity and compliance at HIPAA/GDPR/ISO/NIST depth

Clinical systems integration across EHR/RCM/diagnostics

Operational and financial performance improvement at portfolio scale

I build organizations where innovation is practical, secure, clinically trustworthy, and financially accretive—turning fragmented environments into unified, intelligent ecosystems that improve outcomes, strengthen margin, and enable long-term scale.

Whether stepping in as CEO to drive a turnaround, as CTO/CIO to architect an AI-enabled platform, or as an operating partner to reshape a multi-entity portfolio, my approach is grounded in clarity, disciplined execution, and measurable value creation.

Executive leader with 25+ years driving large-scale transformation across healthcare, MedTech, diagnostics, life sciences, and AI-driven SaaS. Served as CEO, COO, CIO, CTO, and CISO across high-growth companies, PE-backed portfolios, and global clinical enterprises. Built and scaled organizations through AI innovation, digital modernization, operational excellence, clinical integration, cybersecurity, and P&L leadership.

Led companies through turnarounds, rapid scale, M&A integration, regulatory acceleration, and global expansion across 50 U.S. states and 13 countries. Delivered industry-defining results including 40% EBITDA, 84% gross margins, 37% operating margin, $120M+ capital raised, $90M+ M&A, and a 10× MOIC exit.

Architected and launched FDA-cleared SaMD diagnostics, national CPT reimbursement, LLM/NLP clinical systems, predictive AI platforms, IoT diagnostic ecosystems, enterprise cloud architectures, and large-scale EHR/RCM integrations.

As a hybrid operator—strategic, technical, and security-driven—built and led organizations up to 500+ employees, modernized enterprise infrastructures (AWS/Azure/GCP), and achieved 97%+ HIPAA/GDPR/ISO/NIST audit compliance across globally distributed environments. Known for converting complex, fragmented environments into unified, efficient, AI-enabled platforms that drive measurable clinical, operational, and financial outcomes.

MS Biomedical informatics 

BS Business Administration