- Contribute to and lead initiatives to design and analyze engineered mammalian cell lines by developing robust and innovative computational approaches that utilize mechanistic models, multiomics, machine learning, deep learning, and AI.
- Work closely with bench scientists to develop experimental plans and analyze quantitative measurements with statistical rigor to gain biological insights and to train and validate models.
- Regularly dive deep into the multiomics stack to innovate on analysis techniques, algorithms, models.
- Present findings to our team, leadership, and partners.
- Pair with our software engineers to transition impactful computational approaches into our commercial software offerings.
- Contribute to Asimov's long-term computational biology strategy.
- You are a highly skilled researcher and innovator with at least 5 years of experience in industry or academic research and with a published track record of developing new, impactful approaches to computational biology. A strong foundation in statistics and experimental design is a plus.
- You are passionate about joining a startup where teamwork, passion to learn, and excitement to engineer biology take precedence over process and ego.
- You have broad, proven expertise in solving difficult biology problems utilizing both classical and new computational biology approaches, including working with large multiomics datasets, machine learning techniques, deep learning methods, and AI/LLM-based approaches. Demonstrated interest in engineering biology is a plus.
- You have extensive knowledge of molecular biology and cellular biology, particularly in mammalian systems and/or cellular production systems.
- You have deep knowledge of public biological databases and their application for mammalian cell biology.
- You are expert in Python, R, and common bioinformatic toolkits, as well as with computational notebooks (Jupyter), version control (Git), and coding best-practices. You also have experience with cloud computing environments (GCP) and databases (SQL).
- You have a record of working closely with wet lab scientists to design experiments and interpret data to most effectively extract statistically and biologically meaningful insights.
- Experience with developing data applications (Streamlit, PyWebIO, Flask, Dash) is a plus.
-
Computational Biologist
3 weeks ago
GALY Boston, United StatesWe are out of time. Change must be immediate. We have to help the world find alternative ways to produce all the same things we love. But better. Using less land, less water, less energy, and making less waste. If you think that sounds like a mission, well, you are right. We are ...
-
Computational Biologist
3 weeks ago
Biohaven Cambridge, United StatesAt Biohaven, we are committed to improving the lives of patients suffering from neuromuscular disorders by advancing first-in-class and best-in-class therapies. Joining our team now means the opportunity to be a part of disruptive science and innovation for discovering treatments ...
-
Applied Computational Biologist, Renal I
1 week ago
Novartis Cambridge, United States**About the Role**: · Internal Job Title: Senior Expert I, Data Science · Role Location: Cambridge, MA, onsite · About this role: · Key Responsibilities: · - Working closely with a core team of Translational Research & Data Science scientists fluent in wet and dry lab practices · ...
-
Senior Computational Biologist
1 week ago
Pfizer Cambridge, United States Full timeWHY PATIENTS NEED YOU · Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Wh ...
-
Computational Biologist
3 weeks ago
Momentum Biotechnologies Billerica, United StatesMomentum Biotechnologies ("Momentum") is a specialized mass spectrometry services provider and discovery partner to pharma, biopharma, biotech, and gene therapy clients. Our core team of MIT scientists and engineers has been working together since 2000 when they built the RapidFi ...
-
Senior Scientist, Computational Biologist
1 week ago
Harbinger Health Cambridge, United StatesHarbinger Health is pioneering the detection of early cancer and enabling foundationally new approaches to cancer screening, diagnosis, and management. Incubated within Flagship Pioneering for three years before launching in 2021, Harbinger combines advances in artificial intelli ...
-
Associate Computational Biologist, R&D
3 weeks ago
CATALOG Charlestown, United StatesJob Description · Job DescriptionCATALOG, a Boston-based pioneering startup, is making significant strides in the field of data storage and computation by harnessing the power of DNA. DNA, known for its millennia-long stability, unrivaled information density, and cost-effective r ...
-
Applied Computational Biologist, Renal I
3 weeks ago
Novartis CAMBRIDGE, MA, United StatesAbout the roleInternal Job Title: Senior Expert I, Data ScienceRole Location: Cambridge, MA, onsiteAbout this role:Novartis Biomedical Research is our innovation engine where public and private research merge to substantiate novel drug candidates and evaluate novel biomedical tec ...
-
Research Assistant Iii
2 weeks ago
Harvard University Boston, United States**Job Summary** · **About us**: · The Wyss Institute's mission is to transform healthcare and the environment by emulating the way nature builds. We harness the imagination of academia and the focus of industry to translate ground-breaking technologies into commercial products th ...
-
Data Scientist I, Research Sciences
3 weeks ago
Sarepta Therapeutics Cambridge, United StatesThe Data Scientist, Research Sciences role at Sarepta is an exciting opportunity for someone with strong data science and analytical skills who wants to see their work directly impacting patient care. In this hands-on role, the data scientist will research and develop advanced an ...
-
Bioinformaticist (Wiggs, Segre)
1 week ago
Mass. Eye and Ear (MEE) Boston, United States**Bioinformaticist (Wiggs, Segre)** · ***: · If interested, please send your CV, a cover letter describing your previous research experience and future research interests, and contact information for 3 references, to Dr. Janey Wiggs at janey_wiggs [at] and Dr. Ayellet Segrè: aye ...
-
Genomic Data Coordinator
3 weeks ago
Biogen Cambridge, United States**Job Description** About This Role** · In Biogen's Translational Sciences group, we leverage cutting-edge data and insights from human genetics and genomics, multi-omics, disease biology, and real-world patient and population cohorts to identify, validate, and prioritize novel d ...
-
Translational Human Geneticist
1 week ago
Novartis Cambridge, United States**Summary**: · We are seeking a human geneticist who wants to see their hypotheses tested in the lab. We are the Human Genetics and Target team within the Discovery Sciences department. You will be working closely with wet and dry lab team members to discover and advance novel ta ...
-
Translational Human Geneticist
1 week ago
Novartis Cambridge, United States**Summary**: · We are seeking a human geneticist who wants to see their hypotheses tested in the lab. We are the Human Genetics and Target team within the Discovery Sciences department. You will be working closely with wet and dry lab team members to discover and advance novel ta ...
-
Research Assistant Ii
1 week ago
Harvard University Boston, United States**Job Summary** · **About us**: · The Wyss Institute's mission is to transform healthcare and the environment by emulating the way nature builds. We harness the imagination of academia and the focus of industry to translate ground-breaking technologies into commercial products th ...
-
Bristol-Myers Squibb Cambridge, United States**Working with Us** · Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production ...
-
Customer Success Manager
2 days ago
Schrödinger Cambridge, United StatesAs a member of our Enterprise Informatics team, you'll play a vital role in all stages of LiveDesign deployment for customers, from initial project scoping through to long term successful adoption. By serving as the bi-directional voice for these customers, you'll also help drive ...
-
Full Stack Embedded Systems Engineer
4 weeks ago
Metric Bio Boston, United StatesAbout the Client: · Metric Search is delighted to be partnering with a hybrid design and R&D company who fuse design, technology, and biology to invent multi-scale products and environments. This company build a nature-centric approach that delivers design solutions by, for, and ...
-
Molecular Pharmacologist
3 weeks ago
Kojin Therapeutics Boston, United StatesWe are seeking an initiative-taking, creative, and curious scientist to join our growing preclinical pharmacology team. The ideal candidate will have solid molecular pharmacology background related to cancer or other diseases, demonstrated experience in studying mechanisms involv ...
-
Preclinical/Translational Pharmacologist
3 weeks ago
Kojin Therapeutics Boston, United StatesWe are seeking a preclinical/translational pharmacologist with experience in developing oncology small-molecule therapeutics. The ideal candidate would have solid experience in designing and conducting preclinical/translational pharmacology studies and be knowledgeable in molecul ...
Senior/Principal Computational Biologist - Boston, United States - Asimov
Description
Our mission at Asimov is to advance humanity's ability to design living systems, enabling biotechnologies with outsized benefit to society. We're developing a mammalian synthetic biology platform––from cells to software––to enable the design and manufacture of next-generation therapeutics.
We are searching for a Senior or Principal Computational Biologist with an extensive track record of developing innovative approaches that utilize mechanistic models, machine learning, omics, deep learning, and AI (e.g. LLMs). At Asimov, predictive modeling and simulation are core to our platform. We genetically engineer living cells and refine our designs using an ever-expanding suite of computational design methodologies and sophisticated analysis of multiomics data. The ideal candidate is motivated by designing complex cellular systems, distilling insight from large biological datasets, and producing novel tools to be used by others. This is a unique opportunity to work at a nimble, forward-thinking synthetic biology startup and help build the foundation for engineering biology.
About the Role:
About You:
We're fueled by a vision to transform biological engineering into a fully-fledged engineering discipline. Should you join our team, you will grow with a constantly evolving organization and push the frontiers of synthetic biology. Company culture is key to Asimov, and ours is a culture of recombination; we believe that our mission can only be achieved by bringing together a diverse team with a mixture of backgrounds and perspectives.