- Lead biomarker strategies for one or more clinical trials
- Serve as point of contact for all aspects of clinical biomarker strategy providing scientific expertise and leadership to programs
- Partner with clinical and discovery groups to create high quality biomarker strategies in the clinic
- Implement standardized and cutting edge tools to characterize drug mechanisms, implement diagnostic strategies, and inform back translation research
- Leadership of biomarker subteams to enable cross functional collaboration on biomarker implementation
- Author biomarker sections of protocols, ICFs, IRB responses, regulatory documents, and others
- Pro-actively consult primary scientific literature, keep current on state of art technologies and emerging concepts in oncology
- Strong scientific background in tumor biology (cell signaling, DNA damage repair, targeted therapies) and immuno-oncology supported by publication record in these areas
- Clinical development experience interacting with teams conducting clinical trials
- Demonstrated leadership in translational sciences, employing pharmacodynamic, predictive and exploratory biomarkers
- Experience in analysis of large datasets
- Experience in assay development, qualification and implementing biomarker assays on diverse platforms including IHC/IF, gene expression profiling, flow cytometry etc
- Companion diagnostics development experience is a plus
- Effectively work in a cross-functional team environment, interacting with various levels within the organization as well as vendors/academic sites/KOLs
- Organization, orientation to details, and effective time management with an ability to adapt to changing priorities
- Excellent written and oral presentation skills in the English language
- The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
- We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
- This job is eligible to participate in our short-term incentive programs.
- This job is eligible to participate in our long-term incentive programs
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Principal Research Scientist I, Oncology Biomarkers - North Chicago, United States - AbbVie
Description
Job Description
Job DescriptionCompany DescriptionAbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.
Job DescriptionAbbVie Oncology is currently offering a unique opportunity for a highly motivated individual to join our team as a Principal Research Scientist. In this role you will join an experienced team to lead biomarker efforts for Abbvie sponsored clinical trials. To be successful in this role, the ideal candidate will have experience in the development and execution of biomarker strategies in clinical trials. As a member of both research and clinical development project teams he/she will have the opportunity to work in a highly collaborative environment to support projects across all phases of clinical development.
KEY GOALS INCLUDE:
Principal Research Scientist I - BS or equivalent education and extensive, typically 14+ years of experience; MS or equivalent education with typically 12+ years of experience; PhD with typically 6+ years of experience in area or scientific area of discipline
PREFERRED QUALIFICATIONS:
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company's sole and absolute discretion, consistent with applicable law.
AbbVie is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVie's policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.
